CSCI 8725 Databases for Bioinformatics      Spring 2008

 

1.   Administration

·         Class meetings in EECS 3-115 at  02:30 P.M. - 03:45 P.M.  on Tuesdays and Thursdays

·         Instructor: John Carlis     carlis@cs.umn.edu ;

5-225c EE/CSCI;  625-6092; office hour:  Tuesday  1:00 - 2:00 and by appointment

2.      Keeping Score

·         good grooming 0% , tests 0%

·         class participation 10%

·         two 10 minute class lectures 20%;

Most students will talk about a publicly available scientific database
[There are about a thousand.  start here:
http://www.ncbi.nlm.nih.gov/genome/guide/human/

http://www.ncbi.nlm.nih.gov/About/tools/restable_org.html

·         project:  proposal 15%, presentation 15%, report 40% 

·         the project topic is wide open. 

3.    Policies

·         Grades are criterion not reference based.  Therefore, you are competing against a standard, not each other. So talk to each other.

·         Things are due when they are due.

·         Be respectful of each other.

4.    Learning

·         Participate in class.  You will NOT be graded on whether you speak well or poorly.  However, ceterus paribus, mute students generally do worse than active ones.

·         You  must  prepare for class. I'll assume that you have read the material and thought some about it. [By being prepared you will learn more with less effort.] On the course evaluation you will report on how often you were prepared.

·         Mastery doesn’t occur in ten minute units, nor does it always move forward. Read big chunks; reread in context; draw concept diagrams.

 

5.    Approximate Schedule

 

Report or lecture messages and outline due 2 days before you present. 

Final report due when you present

week

Tuesday class

Topic

Readings &resources for Carlis lectures

Stuff

1

1/22

Intro

http://www.ncbi.nlm.nih.gov/About/sitemap.html

http://www.ncbi.nlm.nih.gov/Genbank/genbankstats.html

Become familiar with NCBI

2

1/29

more intro

http://www.ncbi.nlm.nih.gov/About/primer/

 

3

2/5

Genbank

http://www.ncbi.nlm.nih.gov/Sitemap/samplerecord.html

 

 

4

2/12

Talk on talking, PDB, SwisProt, Prosite

http://www.rcsb.org/pdb/

http://mmb.pcb.ub.es/em/PDF/CAPITULO-6/swisprot.htm

http://us.expasy.org/prosite/

 

5

2/18

Go

http://www.geneontology.org/

 

Submit “intent”

6

2/25

Microarrays

www.affymetrix.com

Begin student database talks

7

3/4

Pathways, KEGG

http://www.expasy.org/cgi-bin/search-biochem-index

http://www.genome.jp/kegg/pathway.html

Submit proposal

8

3/11

Proteomics

http://us.expasy.org/

 

 

3/17-3/21

Spring Break

 

 

9

3/25

DBMS extensions

TBA

 

10

4/1

DBMS extensions

TBA

 

11

4/8

Prints

Bind

http://umber.sbs.man.ac.uk/dbbrowser/

www.bind.ca

 

12

4/15

Attend bioinformatics symposium

http://www.binf.umn.edu/bisymp05/

 

13

4/22

SNP

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=snp

 

14

4/29

Student reports

 

 

15

5/6

Student reports